Chapter 9 Liver

  1. Brinckman-Ferguson EL, Biller DS. Ultrasound of the right intercostal space. Vet Clin North Am Small Anim Pract 2009;39:761–81. PUBMED Abstract
  2. Probst A, Kunzel W. Sonographic differentiation of liver lobes in the dog. Wiener Tierärztliche Monatsschrift 1993;80:200–7.
  3. Carlisle CH, Wu JX, Heath TJ. Anatomy of the portal and hepatic veins of the dog: a basis for systematic evaluation of the liver by ultrasonography. Vet Radiol Ultrasound 1995;36:227–33.
  4. Wu JX, Carlisle CH. Ultrasonographic examination of the canine liver based on recognition of hepatic and portal veins. Vet Radiol Ultrasound 1995;36:234–9.
  5. Mwanza T, Miyamoto T, Okumura M, et al. Ultrasonography and angiographic examination of normal canine liver vessels. Jpn J Vet Res 1996;44:179–88. PUBMED Abstract
  6. Wachsberg RH, Angyal EA, Klein DM, et al. Echogenicity of hepatic versus portal vein walls revisited with histologic correlation. J Ultrasound Med 1997;16:807–10. PUBMED Abstract
  7. Ivancić M, Mai W. Qualitative and quantitative comparison of renal versus hepatic ultrasonographic intensity in healthy dogs. Vet Radiol Ultrasound 2008;49:368–73. PUBMED Abstract
  8. Rothuizen J, de Vries-Chalmers Hoynck van Papendrecht R, van den Brom WE. Post prandial and cholecystokinin-induced emptying of the gall bladder in dogs. Vet Rec 1990;126:505–7. PUBMED Abstract
  9. Ramstedt KL, Center SA, Randolph JF, et al. Changes in gallbladder volume in healthy dogs after food was withheld for 12 hours followed by ingestion of a meal or a meal containing erythromycin. Am J Vet Res 2008;69:647–51. PUBMED Abstract
  10. Bromel C, Barthez PY, Leveille R, et al. Prevalence of gallbladder sludge in dogs as assessed by ultrasonography. Vet Radiol Ultrasound 1998;39:206–10. PUBMED Abstract
  11. Tsukagoshi T, Ohno K, Tsukamoto A, et al. Decreased gallbladder emptying in dogs with biliary sludge or gallbladder mucocele. Vet Radiol Ultrasound 2012;53:84–91. PUBMED Abstract
  12. Spalding KA. Gallbladder wall thickness. Vet Radiol Ultrasound 1993;34:270–3.
  13. Hittmair KM, Vielgrader HD, Loupal G. Ultrasonographic evaluation of gallbladder wall thickness in cats. Vet Radiol Ultrasound 2001;42:149–55. PUBMED Abstract
  14. Miller ME, Evans HE. Miller's Anatomy of the dog. 3rd ed. Philadelphia: Saunders; 1993.
  15. Leveille R, Biller DS, Shiroma JT. Sonographic evaluation of the common bile duct in cats. J Vet Intern Med 1996;10:296–9. PUBMED Abstract
  16. Lamb CR, Mahoney PN. Comparison of 3 methods for calculating portal blood flow velocity in dogs using duplex-Doppler ultrasonography. Vet Radiol Ultrasound 1994;35:190–4.
  17. Lamb CR, Burton CA, Carlisle CH. Doppler measurement of hepatic arterial flow in dogs: technique and preliminary findings. Vet Radiol Ultrasound 1999;40:77–81. PUBMED Abstract
  18. Nyland TG, Fisher PE. Evaluation of experimentally induced canine hepatic cirrhosis using duplex Doppler ultrasound. Vet Radiol 1990;31:189–94.
  19. Middleton WD, Kurtz AB, Hertzberg BS. Ultrasound: the requisites. 2nd ed. St. Louis: Mosby; 2004.
  20. Smithenson BT, Mattoon JS, Bonagura JD, et al. Pulsed-wave Doppler ultrasonographic evaluation of hepatic veins during variable hemodynamic states in healthy anesthetized dogs. Am J Vet Res 2004;65:734–40. PUBMED Abstract
  21. Szatmari V, Rothuizen J, Voorhout G. Standard planes for ultrasonographic examination of the portal system in dogs. J Am Vet Med Assoc 2004;224:713–16, 698-719. PUBMED Abstract
  22. Sartor R, Mamprim MJ, Takahira RF, et al. Hemodynamic valuation of the right portal vein in healthy dogs of different body weights. Acta Vet Scand 2010;52:36–41.
  23. Lamb CR, Burton CA. Doppler ultrasonographic assessment of closure of the ductus venosus in neonatal Irish wolfhounds. Vet Rec 2004;155:699–701. PUBMED Abstract
  24. Lohse CL, Suter PF. Functional closure of the ductus venosus during early postnatal life in the dog. Am J Vet Res 1977;38:839–44. PUBMED Abstract
  25. Mwanza T, Miyamoto T, Okumura M, et al. Ultrasonographic evaluation of portal vein hemodynamics in experimentally bile duct ligated dogs. Jpn J Vet Res 1998;45:199–206. PUBMED Abstract
  26. Lamb CR. Ultrasonography of portosystemic shunts in dogs and cats. Vet Clin North Am Small Anim Pract 1998;28:725–53. PUBMED Abstract
  27. d'Anjou MA, Penninck D, Cornejo L, et al. Ultrasonographic diagnosis of portosystemic shunting in dogs and cats. Vet Radiol Ultrasound 2004;45:424–37. PUBMED Abstract
  28. Kantrowitz BM, Nyland TG, Fisher P. Estimation of portal blood flow using duplex real-time and pulsed Doppler ultrasound imaging in the dog. Vet Radiol 1989;222–6.
  29. Terry JD, Rysavy J. Peak systolic velocity and flow volume increase with blood pressure in low resistance systems. J Ultrasound Med 1995;14:199–203. PUBMED Abstract
  30. Mostbeck GH, Gossinger HD, Mallek R, et al. Effect of heart rate on Doppler measurements of resistive index in renal arteries. Radiology 1990;175:511–13. PUBMED Abstract
  31. Pierce ME, Sewell R. Identification of hepatic cirrhosis by duplex Doppler ultrasound value of the hepatic artery resistive index. Australas Radiol 1990;34:331–3. PUBMED Abstract
  32. Vassiliades VG, Ostrow TD, Chezmar JL, et al. Hepatic arterial resistive indices: correlation with the severity of cirrhosis. Abdom Imaging 1993;18:61–5. PUBMED Abstract
  33. Sacerdoti D, Merkel C, Bolognesi M, et al. Hepatic arterial resistance in cirrhosis with and without portal vein thrombosis: relationships with portal hemodynamics. Gastroenterology 1995;108:1152–8. PUBMED Abstract
  34. Tanaka K, Mitsui K, Morimoto M, et al. Increased hepatic arterial blood flow in acute viral hepatitis: assessment by color Doppler sonography. Hepatology 1993; 18:21–7. PUBMED Abstract
  35. Han SH, Rice S, Cohen SM, et al. Duplex Doppler ultrasound of the hepatic artery in patients with acute alcoholic hepatitis. J Clin Gastroenterol 2002;34:573–7. PUBMED Abstract
  36. Platt JF, Rubin JM, Ellis JH. Hepatic artery resistance changes in portal vein thrombosis. Radiology 1995;196: 95–8. PUBMED Abstract
  37. Stell D, Downey D, Marotta P, et al. Prospective evaluation of the role of quantitative Doppler ultrasound surveillance in liver transplantation. Liver Transpl 2004; 10:1183–8. PUBMED Abstract
  38. Uzochukwu LN, Bluth EI, Smetherman DH, et al. Early postoperative hepatic sonography as a predictor of vascular and biliary complications in adult orthotopic liver transplant patients. Am J Roentgenol 2005;185: 1558–70. PUBMED Abstract
  39. Chen W, Facciuto ME, Rocca JP, et al. Doppler ultrasonographic findings on hepatic arterial vasospasm early after liver transplantation. J Ultrasound Med 2006;25: 631–8. PUBMED Abstract
  40. Loisance DY, Peronneau PA, Pellet MM, et al. Hepatic circulation after side-to-side portacaval shunt in dogs: velocity pattern and flow rate changes studied by an ultrasonic velocimeter. Surgery 1973;73:43–52. PUBMED Abstract
  41. Bergman JR. Nodular hyperplasia in the liver of the dog: an association with changes in the Ito cell population. Vet Pathol 1985;22:427–38. PUBMED Abstract
  42. Nyland TG, Hager DA. Sonography of the liver, gallbladder, and spleen. Vet Clin North Am Small Anim Pract 1985;15:1123–48. PUBMED Abstract
  43. Nyland TG, Hager DA, Herring DS. Sonography of the liver, gallbladder, and spleen. Semin Vet Med Surg (Small Anim) 1989;4:13–31. PUBMED Abstract
  44. Stowater JL, Lamb CR, Schelling SH. Ultrasonographic features of canine hepatic nodular hyperplasia. Vet Radiol 1990;31:268–72.
  45. Lamb CR. Abdominal ultrasonography in small animals: examination of the liver, spleen and pancreas. J Small Anim Pract 1990;31:6–15.
  46. Lamb CR. Ultrasonography of the liver and biliary tract. Probl Vet Med 1991;3:555–73. PUBMED Abstract
  47. Cuccovillo A, Lamb CR. Cellular features of sonographic target lesions of the liver and spleen in 21 dogs and a cat. Vet Radiol Ultrasound 2002;43:275–8. PUBMED Abstract
  48. Crevier FR, Wrigley RH. The Sonographic features of splenic lymphoid hyperplasia in 31 dogs: a retrospective study (1980-2000). Vet Radiol Ultrasound 2000; 41:566.
  49. Patnaik AK, Hurvitz AI, Lieberman PH. Canine hepatic neoplasms: a clinicopathologic study. Vet Pathol 1980; 17:553–64. PUBMED Abstract
  50. O'Brien RT, Iani M, Matheson J, et al. Contrast harmonic ultrasound of spontaneous liver nodules in 32 dogs. Vet Radiol Ultrasound 2004;45:547–53. PUBMED Abstract
  51. Ochiai K, Takechi M, Matsumoto T, et al. Human focal nodular hyperplasia-like lesion in the liver of a cat. Jpn J Vet Res 1990;38:117–25. PUBMED Abstract
  52. Nyland TG, Park RD. Hepatic ultrasonography in the dog. Vet Radiol 1983;24:74–84.
  53. Berry CR, Ackerman N, Charach M, et al. Iatrogenic biloma (biliary pseudocyst) in a cat with hepatic lipidosis. Vet Radiol Ultrasound 1992;33:145–9.
  54. McKenna SC, Carpenter JL. Polycystic disease of the kidney and liver in the Cairn Terrier. Vet Pathol 1980; 17:436–42. PUBMED Abstract
  55. McAloose D, Casal M, Patterson DF, et al. Polycystic kidney and liver disease in two related West Highland White Terrier litters. Vet Pathol 1998;35:77–81. PUBMED Abstract
  56. Van den Ingh TS, Rothuizen J. Congenital cystic disease of the liver in seven dogs. J Comp Pathol 1985;95: 405–14. PUBMED Abstract
  57. Gorlinger S, Rothuizen J, Bunch S, et al. Congenital dilatation of the bile ducts (Caroli's disease) in young dogs. J Vet Intern Med 2003;17:28–32. PUBMED Abstract
  58. Last RD, Hill JM, Roach M, et al. Congenital dilatation of the large and segmental intrahepatic bile ducts (Caroli's disease) in two Golden retriever littermates. J S Afr Vet Assoc 2006;77:210–14. PUBMED Abstract
  59. Crowell WA, Hubbell JJ, Riley JC. Polycystic disease in related cats. J Am Vet Med Assoc 1979;175:286–8. PUBMED Abstract
  60. Stebbins KE. Polycystic disease of the kidney and liver in an adult Persian cat. J Comp Pathol 1989;100:327–30. PUBMED Abstract
  61. Biller DS, Chew DJ, DiBartola SP. Polycystic kidney disease in a family of Persian cats. J Am Vet Med Assoc 1990;196:1288–90. PUBMED Abstract
  62. Nyland TG, Koblik PD, Tellyer SE. Ultrasonographic evaluation of biliary cystadenomas in cats. Vet Radiol Ultrasound 1999;40:300–6. PUBMED Abstract
  63. vanSonnenberg E, Simeone JF, Mueller PR, et al. Sonographic appearance of hematoma in the liver, spleen, and kidney: a clinical, pathologic, and animal study. Radiology 1983;147:507–10. PUBMED Abstract
  64. Farrar ET, Washabau RJ, Saunders HM. Hepatic abscesses in dogs: 14 cases (1982-1994). J Am Vet Med Assoc 1996;208:243–7. PUBMED Abstract
  65. Schwarz LA, Penninck DG, Leveille-Webster C. Hepatic abscesses in 13 dogs: a review of the ultrasonographic findings, clinical data and therapeutic options. Vet Radiol Ultrasound 1998;39:357–65. PUBMED Abstract
  66. Grooters AM, Sherding RG, Biller DS, et al. Hepatic abscesses associated with diabetes mellitus in two dogs. J Vet Intern Med 1994;8:203–6. PUBMED Abstract
  67. Konde LJ, Lebel JL, Park RD, et al. Sonographic application in the diagnosis of intraabdominal abscess in the dog. Vet Radiol 1986; 27:151–4.
  68. Downs MO, Miller MA, Cross AR, et al. Liver lobe torsion and liver abscess in a dog. J Am Vet Med Assoc 1998;212:678–80. PUBMED Abstract
  69. Sergeeff JS, Armstrong PJ, Bunch SE. Hepatic abscesses in cats: 14 cases (1985-2002). J Vet Intern Med 2004; 18:295–300. PUBMED Abstract
  70. Singh M, Krockenberger M, Martin P, et al. Hepatocellular carcinoma with secondary abscessation in a cat. Aust Vet J 2005;83:736–9. PUBMED Abstract
  71. Zerem E, Hadzic A. Sonographically guided percutaneous catheter drainage versus needle aspiration in the management of pyogenic liver abscess. AJR Am J Roentgenol 2007;189:W138–42. PUBMED Abstract
  72. Miele V, Buffa V, Stasolla A, et al. Contrast enhanced ultrasound with second generation contrast agent in traumatic liver lesions. Radiol Med (Torino) 2004;108: 82–91. PUBMED Abstract
  73. Catalano O, Lobianco R, Raso MM, et al. Blunt hepatic trauma: evaluation with contrast-enhanced sonography: sonographic findings and clinical application. J Ultrasound Med 2005;24:299–310. PUBMED Abstract
  74. McGahan JP, Horton S, Gerscovich EO, et al. Appearance of solid organ injury with contrast-enhanced sonography in blunt abdominal trauma: preliminary experience. AJR Am J Roentgenol 2006;187:658–66. PUBMED Abstract
  75. Valentino M, Serra C, Pavlica P, et al. Contrast-enhanced ultrasound for blunt abdominal trauma. Semin Ultrasound CT MR 2007;28:130–40. PUBMED Abstract
  76. Tang J, Wenxiu L, Faqin L, et al. Comparison of gray-scale contrast-enhanced ultrasonography with contrast-enhanced computed tomography in different grading of blunt hepatic and splenic trauma: an animal experiment. Ultrasound Med Biol 2009;35:566–75. PUBMED Abstract
  77. Mihalik J, Smith R, Toevs C, et al. The use of contrast-enhanced ultrasound for the evaluation of solid abdominal organ injury in patients with blunt abdominal trauma. J Trauma Acute Care Surg 2012. PUBMED Abstract
  78. Catalano O, Cusati B, Nunziata A, et al. Active abdominal bleeding: contrast enhanced sonography. Abdom Imaging 2006;31:9–16. PUBMED Abstract
  79. Sato AF, Solano M. Radiographic diagnosis: liver lobe entrapment and associated emphysematous hepatitis. Vet Radiol Ultrasound 1998;39:123–4. PUBMED Abstract
  80. Sonnenfield JM, Armbrust LJ, Radlinsky MA, et al. Radiographic and ultrasonographic findings of liver lobe torsion in a dog. Vet Radiol Ultrasound 2001;42:344–6. PUBMED Abstract
  81. Schwartz SG, Mitchell SL, Keating JH, et al. Liver lobe torsion in dogs: 13 cases (1995-2004). J Am Vet Med Assoc 2006;228:242–7. PUBMED Abstract
  82. Swann HM, Brown DC. Hepatic lobe torsion in 3 dogs and a cat. Vet Surg 2001;30:482–6. PUBMED Abstract
  83. Liptak J. Hepatobiliary tumors. In: Withrow SJ, MacEwen EG, editors. Small animal clinical oncology. 4th ed. Philadelphia: WB Saunders; 2007. p. 484–92.
  84. Strombeck DR. Clinicopathologic features of primary and metastatic neoplastic diseases of the liver in dogs. J Am Vet Med Assoc 1978;173:267.
  85. Cullen JM, Popp JA. Tumors of the liver and gall bladder. In: Meuten DJ, editor. Tumors in domestic animals. 4th ed. Ames: Iowa State Press; 2002.
  86. Thamm DH. Hepatobiliary tumors. In: Withrow SJ, MacEwen EG, editors. Small animal clinical oncology. 3rd ed. Philadelphia: WB Saunders; 2001.
  87. Nyman HT, Kristensen AT, Flagstad A, et al. A review of the sonographic assessment of tumor metastases in liver and superficial lymph nodes. Vet Radiol Ultrasound 2004;45:438–48. PUBMED Abstract
  88. Feeney DA, Johnston GR, Hardy RM. Two-dimensional, gray-scale ultrasonography for assessment of hepatic and splenic neoplasia in the dog and cat. J Am Vet Med Assoc 1984;184:68–81. PUBMED Abstract
  89. Whiteley MB, Feeney DA, Whiteley LO, et al. Ultrasonographic appearance of primary and metastatic canine hepatic tumors. A review of 48 cases. J Ultrasound Med 1989;8:621–30. PUBMED Abstract
  90. Hammer AS, Sikkema DA. Hepatic neoplasia in the dog and cat. Vet Clin North Am Small Anim Pract 1995;25:419–35. PUBMED Abstract
  91. Eves NG. Hepatocellular adenoma in a 12-year-old crossbred German shepherd dog. Can Vet J 2004;45:326–8. PUBMED Abstract
  92. Murakami T, Feeney DA, Bahr KL. Analysis of clinical and ultrasonographic data by use of logistic regression models for prediction of malignant versus benign causes of ultrasonographically detected focal liver lesions in dogs. Am J Vet Res 2012;73:821–9. PUBMED Abstract
  93. Guillot M, Danjou MA, Alexander K, et al. Can sonographic findings predict the results of liver aspirates in dogs with suspected liver disease? Vet Radiol Ultrasound 2009;50:513–18. PUBMED Abstract
  94. Nyland TG. Ultrasonic patterns of canine hepatic lymphosarcoma. Vet Radiol 1984;25:167–72.
  95. Nyland TG, Kantrowitz BM. Ultrasound in diagnosis and staging of abdominal neoplasia. Contemp Issues Small Anim Pract 1986;6:1–24.
  96. Lamb CR, Hartzband LE, Tidwell AS, et al. Ultrasonographic findings in hepatic and splenic lymphosarcoma in dogs and cats. Vet Radiol Ultrasound 1991;32:117–20.
  97. Crabtree AC, Spangler E, Beard D, et al. Diagnostic accuracy of gray-scale ultrasonography for the detection of hepatic and splenic lymphoma in dogs. Vet Radiol Ultrasound 2010;51:661–4. PUBMED Abstract
  98. Dank G, Rassnick KM, Kristal O, et al. Clinical characteristics, treatment, and outcome of dogs with presumed primary hepatic lymphoma: 18 cases (1992-2008). J Am Vet Med Assoc 2011;239:966–71. PUBMED Abstract
  99. Faverzani S, Chinosi S, Valenti P, et al. Comparison between ultrasonography and cytology of liver focal lesions and parenchyma in the dog and cat. Vet Res Comm 2006; 30(Suppl. 1):293–6.
  100. Sato AF, Solano M. Ultrasonographic findings in abdominal mast cell disease: a retrospective study of 19 patients. Vet Radiol Ultrasound 2004;45:51–7. PUBMED Abstract
  101. Hanson JA, Papageorges M, Girard E, et al. Ultrasonographic appearance of splenic disease in 101 cats. Vet Radiol Ultrasound 2001;42:441–5. PUBMED Abstract
  102. Stefanello D, Valenti P, Faverzani S. Ultrasound-guided cytology of spleen and liver: A prognostic tool in canine cutaneous mast cell tumor. J Vet Intern Med 2009;23:1051–7. PUBMED Abstract
  103. Book AP, Fidel J, Wills T, et al. Correlation of ultrasound findings, liver and spleen cytology, and prognosis in the clinical staging of high metastatic risk canine mast cell tumors. Vet Radiol Ultrasound 2011;52:548–54.
  104. Cruz-Arambulo R, Wrigley R, Powers B. Sonographic features of histiocytic neoplasms in the canine abdomen. Vet Radiol Ultrasound 2004;45:554–8. PUBMED Abstract
  105. Ramirez S, Douglass JP, Robertson ID. Ultrasonographic features of canine abdominal malignant histiocytosis. Vet Radiol Ultrasound 2002;43:167–70. PUBMED Abstract
  106. Adler R, Wilson DW. Biliary cystadenoma of cats. Vet Pathol 1995;32:415–18. PUBMED Abstract
  107. Trout NJ, Berg RJ, McMillan MC, et al. Surgical treatment of hepatobiliary cystadenomas in cats: five cases (1988-1993). J Am Vet Med Assoc 1995;206:505–7. PUBMED Abstract
  108. Trout NJ. Surgical treatment of hepatobiliary cystadenomas in cats. Semin Vet Med Surg (Small Anim) 1997;12:51–3. PUBMED Abstract
  109. Warren-Smith CMR, Andrew S, Mantis P, et al. Lack of associations between ultrasonographic appearance of parenchymal lesions of the canine liver and histological diagnosis. J Small Anim Pract 2012;53:168–73. PUBMED Abstract
  110. Newell SM, Selcer BA, Girard E, et al. Correlations between ultrasonographic findings and specific hepatic diseases in cats: 72 cases (1985-1997). J Am Vet Med Assoc 1998;213:94–8. PUBMED Abstract
  111. Wang KY, Panciera DL, Al-Rukibat RK, et al. Accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats: 97 cases (1990-2000). J Am Vet Med Assoc 2004;224:75–8. PUBMED Abstract
  112. Taylor KJW. Gastrointestinal Doppler ultrasound. In: Taylor KJW, Burns PN, Wells PNT, editors. Clinical applications of Doppler ultrasound. New York: Raven Press; 1988. p. 162–200.
  113. Taylor KJ, Ramos I, Carter D, et al. Correlation of Doppler US tumor signals with neovascular morphologic features. Radiology 1988;166:57–62. PUBMED Abstract
  114. Bates SM, Keller MS, Ramos IM, et al. Hepatoblastoma: detection of tumor vascularity with duplex Doppler US. Radiology 1990;176:505–7. PUBMED Abstract
  115. Orr NM, Taylor KJW. Doppler detection of tumor vascularity. Clin Diagn Ultrasound 1990;26:149–63. PUBMED Abstract
  116. Cosgrove DO, Bamber JC, Davey JB, et al. Color Doppler signals from breast tumors. Work in progress. Radiology 1990;176:175–80. PUBMED Abstract
  117. Dock W, Grabenwoger F, Metz V, et al. Tumor vascularization: assessment with duplex sonography. Radiology 1991;181:241–4. PUBMED Abstract
  118. Tanaka S, Kitamura T, Fujita M, et al. Color Doppler flow imaging of liver tumors. AJR Am J Roentgenol 1990;154:509–14. PUBMED Abstract
  119. Numata K, Tanaka K, Mitsui K, et al. Flow characteristics of hepatic tumors at color Doppler sonography: correlation with arteriographic findings. AJR Am J Roentgenol 1993;160:515–21. PUBMED Abstract
  120. Murphy KJ, Rubin JM. Power Doppler: it's a good thing. Semin Ultrasound CT MR 1997;18:13–21. PUBMED Abstract
  121. Bartolozzi C, Lencioni R, Paolicchi A, et al. Differentiation of hepatocellular adenoma and focal nodular hyperplasia of the liver: comparison of power Doppler imaging and conventional color Doppler sonography. Eur Radiol 1997;7:1410–15. PUBMED Abstract
  122. Martinoli C, Pretolesi F, Crespi G, et al. Power Doppler sonography: clinical applications. Eur J Radiol 1998; 27(Suppl. 2):S133–40. PUBMED Abstract
  123. Hosten N, Puls R, Lemke AJ, et al. Contrast-enhanced power Doppler sonography: improved detection of characteristic flow patterns in focal liver lesions. J Clin Ultrasound 1999;27:107–15. PUBMED Abstract
  124. Hirai T, Ohishi H, Yamada R, et al. Three-dimensional power Doppler sonography of tumor vascularity. Radiat Med 1998;16:353–7.
  125. Nyman HT, Kristensen AT, Flagstad A. A review of the sonographic assessment of tumor metastases in liver and superficial lymph nodes. Vet Radiol Ultrasound 2004; 45:438–48. PUBMED Abstract
  126. Ziegler LE, O'Brien RT, Waller KR, et al. Quantitative contrast harmonic ultrasound imaging of normal canine liver. Vet Radiol Ultrasound 2003;44:451–4. PUBMED Abstract
  127. Ohlerth S, O'Brien RT. Contrast ultrasound: general principles and veterinary clinical applications. Vet J 2007;174:501–12. PUBMED Abstract
  128. O'Brien RT, Holmes SP. Recent advances in ultrasound technology. Clin Tech Small Anim Pract 2007;22: 93–103. PUBMED Abstract
  129. Haers H, Saunders JH. Review of clinical characteristics and applications of contrast-enhanced ultrasonography in dogs. J Am Vet Med Assoc 2009;234:460–70. PUBMED Abstract
  130. Kutara K, Asano K, Kito A, et al. Contrast harmonic imaging of canine hepatic tumors. J Vet Med Sci 2006; 68:433–8. PUBMED Abstract
  131. O'Brien RT. Improved detection of metastatic hepatic hemangiosarcoma nodules with contrast ultrasound in three dogs. Vet Radiol Ultrasound 2007;48:146–8. PUBMED Abstract
  132. Ivančić M, Long F, Seiler G. Contrast harmonic ultrasonography of splenic masses and associated liver nodules in dogs. J Am Vet Med Assoc 2009;234:88–94.
  133. Kanemoto H, Ohno K, Nakashima K, et al. Characterization of canine focal liver lesion with contrast-enhanced ultrasound using a novel contrast agent—Sonozoid. Vet Radiol Ultrasound 2009;50:188–94. PUBMED Abstract
  134. Nakamura K, Takagi S, Sasaki N, et al. Contrast-enhanced ultrasonography for characterization of canine focal liver lesions. Vet Radiology Ultrasound 2010;51:79–85. PUBMED Abstract
  135. Kanemoto H, Ohno K, Nakashima K, et al. Vascular and Kupffer imaging of canine liver and spleen using the new contrast agent Sonozoid. J Vet Med Sci 2008;70: 1265–8. PUBMED Abstract
  136. Leinonen MR, Raekallio MR, Vainio OM, et al. Quantitative contrast-enhanced ultrasonographic analysis of perfusion in the kidneys, liver, pancreas, small intestine, and mesenteric lymph nodes in healthy cats. Am J Vet Res 2010;71:1305–11. PUBMED Abstract
  137. Janica JR, Serwatka W, Polakow J, et al. Evaluation of enhancement patterns of focal nodular hyperplasia in contrast-enhanced, wide-band phase-inversion harmonic power Doppler imaging of the liver. Med Sci Monit 2004;10(Suppl. 3):17–21. PUBMED Abstract
  138. Janica JR, Serwatka W, Polakow J, et al. Hemangiomas and focal nodular hyperplasia images in contrast-enhanced, wide-band phase-inversion harmonic power Doppler imaging. Med Sci Monit 2004;10(Suppl. 3): 26–31. PUBMED Abstract
  139. Kim AY, Choi BI, Kim TK, et al. Hepatocellular carcinoma: power Doppler US with a contrast agent— preliminary results. Radiology 1998;209:135–40. PUBMED Abstract
  140. Strobel D, Kleinecke C, Hansler J, et al. Contrast-enhanced sonography for the characterisation of hepatocellular carcinomas—correlation with histological differentiation. Ultraschall Med 2005;26:270–6. PUBMED Abstract
  141. Genadieva-Dimitrova M, Neskovski M, Popova R, et al. Contrast-enhanced power Doppler sonography in detection and differentiation of focal liver lesions. Prilozi 2005;26:41–9. PUBMED Abstract
  142. Du WH, Yang WX, Xiong XQ, et al. Contrast-enhanced ultrasonographic imaging diagnosis on assessment of vascularity in liver metastatic lesions. World J Gastroenterol 2005;11:3610–13. PUBMED Abstract
  143. Lee JY, Choi BI, Han JK, et al. State-of-the-art ultrasonography of hepatocellular carcinoma. Eur J Radiol 2006;58:177–85. PUBMED Abstract
  144. Wisner ER, Ferrara KW, Short RE, et al. Sentinel node detection using contrast-enhanced power Doppler ultrasound lymphography. Invest Radiol 2003;38:358–65. PUBMED Abstract
  145. Salwei RM, O'Brien RT, Matheson JS. Characterization of lymphomatous lymph nodes in dogs using contrast harmonic and Power Doppler ultrasound. Vet Radiol Ultrasound 2005;46:411–16. PUBMED Abstract
  146. Lurie DM, Seguin B, Schneider PD, et al. Contrast-assisted ultrasound for sentinel lymph node detection in spontaneously arising canine head and neck tumors. Invest Radiol 2006;41:415–21. PUBMED Abstract
  147. Feeney DA, Anderson KL, Ziegler LE. Statistical relevance of ultrasonographic criteria in the assessment of diffuse liver disease in dogs and cats. Am J Vet Res 2008;69:212–21. PUBMED Abstract
  148. Drost WT, Henry GA, Memkoth JH, et al. Quantification of hepatic and renal cortical echogenicity in clinically normal cats. Am J Vet Res 2000;61:1016–20, 45, 52. PUBMED Abstract
  149. Biller DS, Kantrowitz B, Miyabayashi T. Ultrasonography of diffuse liver disease. A review. J Vet Intern Med 1992;6:71–6. PUBMED Abstract
  150. Wrigley RH. Radiographic and ultrasonographic diagnosis of liver diseases in dogs and cats. Vet Clin North Am Small Anim Pract 1985;15:21–38. PUBMED Abstract
  151. Lamb CR, Hartzband LE, Tidwell AS, et al. Ultrasonographic findings in hepatic and splenic lymphosarcoma in dogs and cats. Vet Radiol 1991;32:117–20.
  152. Yeager AE, Mohammed H. Accuracy of ultrasonography in the detection of severe hepatic lipidosis in cats. Am J Vet Res 1992;53:597–9. PUBMED Abstract
  153. Nicoll RG, O'Brien RT, Jackson MW. Qualitative ultrasonography of the liver in obese cats. Vet Radiol Ultrasound 1998;39:47–50. PUBMED Abstract
  154. O'Brien RT, Zagzebski JA, Lu ZF, et al. Measurement of acoustic backscatter and attenuation in the liver of dogs with experimentally induced steroid hepatopathy. Am J Vet Res 1996;57:1690–4. PUBMED Abstract
  155. Lu ZF, Zagzebski JA, O'Brien RT, et al. Ultrasound attenuation and backscatter in the liver during prednisone administration. Ultrasound Med Biol 1997;23:1–8. PUBMED Abstract
  156. Syakalima M, Takiguchi M, Yasuda J, et al. Comparison of attenuation and liver-kidney contrast of liver ultrasonographs with histology and biochemistry in dogs with experimentally induced steroid hepatopathy. Vet Q 1998;20:18–22. PUBMED Abstract
  157. Gagne JM, Armstrong PJ, Weiss DJ, et al. Clinical features of inflammatory liver disease in cats: 41 cases (1983-1993). J Am Vet Med Assoc 1999;214:513–16. PUBMED Abstract
  158. Nicoll RG, Jackson MW, Knipp BS, et al. Quantitative ultrasonography of the liver in cats during obesity induction and dietary restriction. Res Vet Sci 1998;64:1–6. PUBMED Abstract
  159. Armstrong PJ, Blanchard G. Hepatic lipidosis in cats. Vet Clin Small Anim 2009;39:599–616. PUBMED Abstract
  160. Penninck D, Berry C. Liver imaging in the cat. Semin Vet Med Surg (Small Anim) 1997;12:10–21. PUBMED Abstract
  161. Marolf AJ, Leach L, Gibbons DS, et al. Ultrasonographic findings of feline cholangitis. J Am Anim Hosp Assoc 2012;48:36–42. PUBMED Abstract
  162. Center SA. Diseases of the gallbladder and biliary tree. Vet Clin Small Anim 2009;39:543–98. PUBMED Abstract
  163. Beatty JA, Barrs VR, Martin PA, et al. Spontaneous hepatic rupture in six cats with systemic amyloidosis. J Small Anim Pract 2002;43:355–63. PUBMED Abstract
  164. Flatland B, Moore RR, Wolf CM, et al. Liver aspirate from a Shar Pei dog. Vet Clin Pathol 2007;36:105–8. PUBMED Abstract
  165. Jacobson LS, Kirberger RM, Nesbit JW. Hepatic ultrasonography and pathological findings in dogs with hepatocutaneous syndrome: new concepts. J Vet Intern Med 1995;9:399–404. PUBMED Abstract
  166. Nyland TG, Barthez PY, Ortega TM, et al. Hepatic ultrasonographic and pathologic findings in dogs with canine superficial necrolytic dermatitis. Vet Radiol Ultrasound 1996;37:200–4.
  167. Hill PB, Auxilia ST, Munro E, et al. Resolution of skin lesions and long-term survival in a dog with superficial necrolytic dermatitis and liver cirrhosis. J Small Anim Pract 2000;41:519–23. PUBMED Abstract
  168. Byrne KP. Metabolic epidermal necrosis-hepatocutaneous syndrome. Vet Clin North Am Small Anim Pract 1999;29:1337–55. PUBMED Abstract
  169. Day MJ. Review of thymic pathology in 30 cats and 36 dogs. J Small Anim Pract 1997;38:393–403. PUBMED Abstract
  170. Godfrey DR, Rest JR. Suspected necrolytic migratory erythema associated with chronic hepatopathy in a cat. J Small Anim Pract 2000;41:324–8. PUBMED Abstract
  171. Kimmel SE, Christiansen W, Byrne KP. Clinicopathological, ultrasonographic, and histopathological findings of superficial necrolytic dermatitis with hepatopathy in a cat. J Am Anim Hosp Assoc 2003;39:23–7. PUBMED Abstract
  172. Bahr A, Wrigley R, Salman M. Quantitative evaluation of imagent as an abdominal ultrasound contrast medium in dogs. Vet Radiol Ultrasound 2000;41:50–5. PUBMED Abstract
  173. Nyman HT, Kristensen AT, Kjelgaard-Hansen M, et al. Contrast-enhanced ultrasonography in normal canine liver. Evaluation of imaging and safety parameters. Vet Radiol Ultrasound 2005;46:243–50. PUBMED Abstract
  174. Moentk J, Biller DS. Bilobed gallbladder in a cat: ultrasonographic appearance. Vet Radiol Ultrasound 1993;34:354–6.
  175. Moores AL, Gregory SP. Duplex gall bladder associated with choledocholithiasis, cholecystitis, gall bladder rupture and septic peritonitis in a cat. J Small Anim Pract 2007;48:404–9. PUBMED Abstract
  176. Liptak JM, Swinney GR, Rothwell TL, et al. Aplasia of the gallbladder in a dog. J Small Anim Pract 2000;41:175–7. PUBMED Abstract
  177. Austin B, Tillson DM, Kuhnt LA. Gallbladder agenesis in a Maltese dog. J Am Anim Hosp Assoc 2006;42:308–11. PUBMED Abstract
  178. Kealy JK, McAllister H. The abdomen. In: Diagnostic radiology & ultrasonography of the dog and cat. 4th ed. St. Louis: Elsevier Saunders; 2005. p. 21–171.
  179. Ralls PW, Quinn MF, Juttner HU, et al. Gallbladder wall thickening: patients without intrinsic gallbladder disease. Am J Roentgenol 1981;137:65–8. PUBMED Abstract
  180. Shlaer WJ, Leopold GR, Scheible FW. Sonography of the thickened gallbladder wall: a nonspecific finding. Am J Roentgenol 1981;136:337–9. PUBMED Abstract
  181. Wegener M, Borsch G, Schneider J, et al. Gallbladder wall thickening: a frequent finding in various nonbiliary disorders—a prospective ultrasonographic study. J Clin Ultrasound 1987;15:307–12. PUBMED Abstract
  182. Reference deleted in proof.
  183. van Breda Vriesman AC, Engelbrecht MR, Smithuis RHM, et al. Diffuse gallbladder wall thickening: differential diagnosis. AJR Am J Roentgenol 2007;188:495–501. PUBMED Abstract
  184. Quantz JE, Miles MS, Reed AL, et al. Elevation of alanine transaminase and gallbladder wall abnormalities as biomarkers of anaphylaxis in canine hypersensitivity patients. J Vet Emerg Crit Care (San Antonio) 2009;19:536–44. PUBMED Abstract
  185. Willard MD, Dunstan RW, Faulkner J. Neuroendocrine carcinoma of the gallbladder in a dog. J Am Vet Med Assoc 1988;192:926–8. PUBMED Abstract
  186. Bromel C, Smeak DD, Leveille R. Porcelain gallbladder associated with primary biliary adenocarcinoma in a dog. J Am Vet Med Assoc 1998;213:1137–9, 1131. PUBMED Abstract
  187. Morrell CN, Volk MV, Mankowski JL. A carcinoid tumor in the gallbladder of a dog. Vet Pathol 2002;39:756–8. PUBMED Abstract
  188. Pazzi P, Gamberini S, Buildrini P. Biliary sludge; the sluggish gallbladder. Dig Liver Dis 2003;35(Suppl. 3):S39–45. PUBMED Abstract
  189. Eich CS, Ludwig LL. The surgical treatment of cholelithiasis in cats: a study of nine cases. J Am Anim Hosp Assoc 2002;38:290–6. PUBMED Abstract
  190. Kirpensteijn J, Fingland RB, Ulrich T, et al. Cholelithiasis in dogs: 29 cases (1980-1990). J Am Vet Med Assoc 1993;202:1137–42. PUBMED Abstract
  191. Fahie MA, Martin RA. Extrahepatic biliary tract obstruction: a retrospective study of 45 cases (1983-1993). J Am Anim Hosp Assoc 1995;31:478–82. PUBMED Abstract
  192. Voros K, Nemeth T, Vrabely T, et al. Ultrasonography and surgery of canine biliary diseases. Acta Vet Hung 2001;49:141–54. PUBMED Abstract
  193. Elwood CM, White RN, Freeman K, et al. Cholelithiasis and hyperthyroidism in a cat. J Feline Med Surg 2001;3:247–52. PUBMED Abstract
  194. Ward R. Obstructive cholelithiasis and cholecystitis in a keeshond. Can Vet J 2006;47:1119–21. PUBMED Abstract
  195. Harvey AM, Holt PE, Barr FJ, et al. Treatment and long-term follow-up of extrahepatic biliary obstruction with bilirubin cholelithiasis in a Somali cat with pyruvate kinase deficiency. J Feline Med Surg 2007;9:424–31. PUBMED Abstract
  196. vanGeffen C, Savary-Bataille K, Chiers K, et al. Bilirubin cholelithiasis and haemosiderosis in an anaemic pyruvate kinase-deficient Somali cat. J Small Anim Pract 2008;49:479–82. PUBMED Abstract
  197. Smith SA, Biller DS, Kraft SL, et al. Diagnostic imaging of biliary obstruction. Comp Cont Ed Pract Vet 1998; 213:94–8.
  198. Kipnis RM. Cholelithiasis, gallbladder perforation, and bile peritonitis in a dog. Canine Pract 1986;13:15–27.
  199. Bromel C, Leveille R, Scrivani PV, et al. Gallbladder perforation associated with cholelithiasis and cholecystitis in a dog. J Small Anim Pract 1998;39:541–4. PUBMED Abstract
  200. Gaillot HA, Penninck DG, Webster CR, et al. Ultrasonographic features of extrahepatic biliary obstruction in 30 cats. Vet Radiol Ultrasound 2007;48:439–47. PUBMED Abstract
  201. Rivers BJ, Walter PA, Johnston GR, et al. Acalculous cholecystitis in four canine cases: ultrasonographic findings and use of ultrasonographic-guided, percutaneous cholecystocentesis in diagnosis. J Am Anim Hosp Assoc 1997;33:207–14. PUBMED Abstract
  202. Oswald GP, Twedt DC, Steyn P. Campylobacter jejuni bacteremia and acute cholecystitis in two dogs. J Am Anim Hosp Assoc 1994;30:165–9.
  203. Ralls PW, Halls J, Lapin SA, et al. Prospective evaluation of the sonographic Murphy sign in suspected acute cholecystitis. J Clin Ultrasound 1982;10:113–15. PUBMED Abstract
  204. Simeone JF, Brink JA, Mueller PR, et al. The sonographic diagnosis of acute gangrenous cholecystitis: importance of the Murphy sign. Am J Roentgenol 1989;152: 289–90. PUBMED Abstract
  205. Lee FT Jr, DeLone DR, Bean DW, et al. Acute cholecystitis in an animal model: findings on color Doppler sonography. AJR Am J Roentgenol 1995;165:85–90. PUBMED Abstract
  206. Zawie DA, Garvey MS. Feline hepatic disease. Vet Clin North Am Small Anim Pract 1984;14:1201–30. PUBMED Abstract
  207. Callahan JE, Haddad JL, Brown DC, et al. Feline cholangitis: a necropsy study of 44 cats (1986-2008). J Feline Med Surg 2011;13:570–6. PUBMED Abstract
  208. Brain PH, Barrs VR, Martin P, et al. Feline cholecystitis and acute neutrophilic cholangitis: clinical findings, bacterial isolates and response to treatment in six cases. J Feline Medicine and Surgery 2006;8:91–103. PUBMED Abstract
  209. Neel JA, Tarigo J, Grindem CB. Gallbladder aspirate from a dog. Vet Clin Pathol 2006;35:467–70. PUBMED Abstract
  210. Armstrong JA, Taylor SM, Tryon KA, et al. Emphysematous cholecystitis in a Siberian Husky. Can Vet J 2000; 41:60–2. PUBMED Abstract
  211. Lord PF, Wilkins RJ. Emphysema of the gallbladder in a diabetic dog. J Am Vet Radiol Soc 1972;13:49–52.
  212. Burk RL, Johnson GF. Emphysematous cholecystitis in the nondiabetic dog: three case histories. Vet Radiol 1980;21:242–5.
  213. Avgeris S, Hoskinson JJ. Emphysematous cholecystitis in a dog: a radiographic diagnosis. J Am Anim Hosp Assoc 1992;28:344–6.
  214. Church EM, Matthiesen DT. Surgical treatment of 23 dogs with necrotizing cholecystitis. J Am Anim Hosp Assoc 1988;24:305–10.
  215. Holt DE, Mehler SJ, Mayhew PD, et al. Canine gallbladder infarction: 12 cases (1993-2003). Vet Pathol 2004;41: 416–18. PUBMED Abstract
  216. Jeffrey RB, Laing FC, Wong W, et al. Gangrenous cholecystitis: diagnosis by ultrasound. Radiology 1983;148: 219–21. PUBMED Abstract
  217. Lipowitz AJ, Poffenbarger E. Gallbladder perforation in a dog. J Am Vet Med Assoc 1984;184:836–9. PUBMED Abstract
  218. Aguirre AL, Center SA, Randolph JF, et al. Gallbladder disease in Shetland Sheepdogs: 38 cases (1995-2005). J Am Vet Med Assoc 2007;231:79–88. PUBMED Abstract
  219. Mealey K, Minch J, White S, et al. An insertion mutation in ABCB4 is associated with gallbladder mucocele formation in dogs. Comp Hepatol 2010;9:1–6. PUBMED Abstract
  220. Kook PH, Schallenberg S, Rentsch KM, et al. Effect of twice-daily oral administration of hydrocortisone on the bile acids composition of gallbladder bile in dogs. Am J Vet Res 2011;72:1607–12. PUBMED Abstract
  221. Mesich ML, Mayhew PD, Paek M, et al. Gallbladder mucoceles and their association with endocrinopathies in dogs: a retrospective case-control study. J Small Anim Pract 2009;50:630–5. PUBMED Abstract
  222. Newell SM, Selcer BA, Mahaffey MB, et al. Gallbladder mucocele causing biliary obstruction in two dogs: ultrasonographic, scintigraphic, and pathological findings. J Am Anim Hosp Assoc 1995;31:467–72. PUBMED Abstract
  223. Besso JG, Wrigley RH, Gliatto JM, et al. Ultrasonographic appearance and clinical findings in 14 dogs with gallbladder mucocele. Vet Radiol Ultrasound 2000;41: 261–71. PUBMED Abstract
  224. Pike FS, Berg J, King NW, et al. Gallbladder mucocele in dogs: 30 cases (2000-2002). J Am Vet Med Assoc 2004; 224:1615–22. PUBMED Abstract
  225. Crews LJ, Feeney DA, Jessen CR, et al. Clinical, ultrasonographic, and laboratory findings associated with gallbladder disease and rupture in dogs: 45 cases (1997-2007). J Am Vet Med Assoc 2009;234:359–66. PUBMED Abstract
  226. Worley DR, Hottinger HA, Lawrence HJ. Surgical management of gallbladder mucoceles in dogs: 22 cases (1999-2003). J Am Vet Med Assoc 2004;225: 1418–22. PUBMED Abstract
  227. Vielgrader HD. Sonographische und klinische diagnostik bei gallenblasen-und gallengangserkrankungen der katze [dissertation]. Veterninarmedizinische Universitat Wien; 1998.
  228. Bennett SL, Milne M, Slocombe RF, et al. Gallbladder mucocoele and concurrent hepatic lipidosis in a cat. Aust Vet J 2007;85:397–400. PUBMED Abstract
  229. Walter R, Dunn ME, d'Anjou MA, et al. Nonsurgical resolution of gallbladder mucocele in two dogs. J Am Vet Med Assoc 2008;232:1688–93. PUBMED Abstract
  230. Voros K, Sterczer A, Manczur F, et al. Percutaneous ultrasound-guided cholecystocentesis in dogs. Acta Vet Hung 2002;50:385–93. PUBMED Abstract
  231. Savary-Bataille KC, Bunch SE, Spaulding KA, et al. Percutaneous ultrasound-guided cholecystocentesis in healthy cats. J Vet Intern Med 2003;17:298–303. PUBMED Abstract
  232. Herman BA, Brawer RS, Murtaugh RJ, et al. Therapeutic percutaneous ultrasound-guided cholecystocentesis in three dogs with extrahepatic biliary obstruction and pancreatitis. J Am Vet Med Assoc 2005;227:1782–6. PUBMED Abstract
  233. Ginat D, Saad WE. Cholecystostomy and transcholecystic biliary access. Tech Vasc Interv Radiol 2008;11: 2–13. PUBMED Abstract
  234. vanSonnenberg E, D'Agostino HB, Goodacre BW, et al. Percutaneous gallbladder puncture and cholecystostomy: results, complications, and caveats for safety. Radiology 1992;183:167–70. PUBMED Abstract
  235. Gold JA, Zeman RK, Schwartz A. Computed tomographic cholangiography in a canine model of biliary obstruction. Invest Radiol 1979;14:498–501. PUBMED Abstract
  236. Raptopoulos V, Fabian TM, Silva W, et al. The effect of time and cholecystectomy on experimental biliary tree dilatation. A multi-imaging evaluation. Invest Radiol 1985;20:276–86. PUBMED Abstract
  237. Boothe HW, Boothe DM, Komkov A, et al. Use of hepatobiliary scintigraphy in the diagnosis of extrahepatic biliary obstruction in dogs and cats: 25 cases (1982- 1989). J Am Vet Med Assoc 1992;201:134–41. PUBMED Abstract
  238. Head LL, Daniel GB. Correlation between hepatobiliary scintigraphy and surgery or postmortem examination findings in dogs and cats with extrahepatic biliary obstruction, partial obstruction, or patency of the biliary system: 18 cases (1995-2004). J Am Vet Med Assoc 2005;227:1618–24. PUBMED Abstract
  239. Foley WD, Quiroz FA. The role of sonography in imaging of the biliary tract. Ultrasound Q 2007;23:123–35. PUBMED Abstract
  240. Watanabe Y, Nagayama M, Okumura A, et al. MR imaging of acute biliary disorders. Radiographics 2007;27:477–95. PUBMED Abstract
  241. Fried AM, Bell RM, Bivins BA. Biliary obstruction in a canine model: sequential study of the sonographic threshold. Invest Radiol 1981;16:317–19. PUBMED Abstract
  242. Zeman RK, Taylor KJ, Rosenfield AT, et al. Acute experimental biliary obstruction in the dog: sonographic findings and clinical implications. AJR Am J Roentgenol 1981;136:965–7. PUBMED Abstract
  243. Nyland TG, Gillett NA. Sonographic evaluation of experimental bile duct ligation in the dog. Vet Radiol 1982;23:252–60.
  244. Finn ST, Park RD, Twedt DC, et al. Ultrasonographic assessment of sincalide-induced canine gallbladder emptying: an aid to the diagnosis of biliary obstruction. Vet Radiol 1991;32:269–76.
  245. Della Santa D, Schweighauser A, Forterre F, et al. Imaging diagnosis—extrahepatic biliary tract obstruction secondary to a duodenal foreign body in a cat. Vet Radiol Ultrasound 2007;48:448–50. PUBMED Abstract
  246. Buote NJ, Mitchell SL, Penninck D, et al. Cholecystoenterostomy for treatment of extrahepatic biliary tract obstruction in cats: 22 cases (1994-2003). J Am Vet Med Assoc 2006;228:1376–82. PUBMED Abstract
  247. Mayhew PD, Holt DE, McLear RC, et al. Pathogenesis and outcome of extrahepatic biliary obstruction in cats. J Small Anim Pract 2002;43:247–53. PUBMED Abstract
  248. Finn-Bodner ST, Park RD, Tyler JW, et al. Ultrasonographic determination, in vitro and in vivo, of canine gallbladder volume, using four volumetric formulas and stepwise-regression models. Am J Vet Res 1993;54:832–5. PUBMED Abstract
  249. Atalan G, Barr FJ, Holt PE. Estimation of the volume of the gall bladder of 32 dogs from linear ultrasonographic measurements. Vet Rec 2007;160:118–22. PUBMED Abstract
  250. Diana A, Guglielmini C, Specchi S, et al. Ultrasonographic evaluation of preprandial and postprandial gallbladder volume in healthy cats. Am J Vet Res 2012;73:1583–8. PUBMED Abstract
  251. Foley P, Miller L, Graham K, et al. Cholecystadenocarcinoma in a cat. Can Vet J 1998;39:373–4. PUBMED Abstract
  252. Patnaik AK, Lius K, Hurvitz AI, et al. Nonhematopoietic neoplasms in cats. J Natl Cancer Inst 1975;54:855–60. PUBMED Abstract
  253. Patnaik AK, Hurvitz AI, Lieberman PH, et al. Canine bile duct carcinoma. Vet Pathol 1981;18:439–44. PUBMED Abstract
  254. Bhandal J, Head L, Francie DA, et al. Use of color flow Doppler ultrasonography to diagnose a bleeding neuroendocrine tumor in the gallbladder of a dog. J Am Vet Med Assoc 2009;235:1326–9. PUBMED Abstract
  255. von Bibra H, Schober K, Jenni R, et al. Diagnosis of constrictive pericarditis by pulsed Doppler echocardiography of the hepatic vein. Am J Cardiol 1989;63:483–8. PUBMED Abstract
  256. Sasson Z, Gupta MK. Are hepatic pulsations in dilated cardiomyopathy with heart failure due to tricuspid regurgitation? Am J Cardiol 1993;71:355–8. PUBMED Abstract
  257. Jullien T, Valtier B, Hongnat JM, et al. Incidence of tricuspid regurgitation and vena caval backward flow in mechanically ventilated patients. A color Doppler and contrast echocardiographic study. Chest 1995;107:488–93. PUBMED Abstract
  258. Minich LL, Tani LY, Shaddy RE, et al. Doppler systemic venous flow patterns: changes in children with mild/moderate pulmonic stenosis. J Am Soc Echocardiogr 1996;9:814–18. PUBMED Abstract
  259. Mehta A, Mehta M, Jain AC. Constrictive pericarditis. Clin Cardiol 1999;22:334–44. PUBMED Abstract
  260. Szatmari V, Sotonyi P, Fenyves B, et al. Doppler-ultrasonographic detection of retrograde pulsatile flow in the caudal vena cava of a puppy with cor triatriatum dexter. Vet Rec 2000;147:68–72. PUBMED Abstract
  261. Sakai K, Nakamura K, Satomi G, et al. Evaluation of tricuspid regurgitation by blood flow pattern in the hepatic vein using pulsed Doppler technique. Am Heart J 1984;108:516–23. PUBMED Abstract
  262. Abu-Yousef MM. Duplex Doppler sonography of the hepatic vein in tricuspid regurgitation. AJR Am J Roentgenol 1991;156:79–83. PUBMED Abstract
  263. Nelson NC, Drost WT, Lerche P, et al. Noninvasive estimation of central venous pressure in anesthetized dogs by measurement of hepatic venous blood flow velocity and abdominal venous diameter. Vet Radiol Ultrasound 2010;51:313–23. PUBMED Abstract
  264. Hosoki T, Kuroda C, Tokunaga K, et al. Hepatic venous outflow obstruction: evaluation with pulsed duplex sonography. Radiology 1989;170:733–7. PUBMED Abstract
  265. Cohn LA, Spaulding KA, Cullen JM, et al. Intrahepatic postsinusoidal venous obstruction in a dog. J Vet Intern Med 1991;5:317–21. PUBMED Abstract
  266. Cave TA, Martineau H, Dickie A, et al. Idiopathic hepatic veno-occlusive disease causing Budd-Chiari–like syndrome in a cat. J Small Anim Pract 2002;43:411–15. PUBMED Abstract
  267. Fine DM, Olivier NB, Walshaw R, et al. Surgical correction of late-onset Budd-Chiari-like syndrome in a dog. J Am Vet Med Assoc 1998;212:835–7. PUBMED Abstract
  268. Schoeman JP, Stidworthy MF. Budd-Chiari-like syndrome associated with an adrenal phaeochromocytoma in a dog. J Small Anim Pract 2001;42:191–4. PUBMED Abstract
  269. Baig MA, Gemmill T, Hammond G, et al. Budd-Chiari–like syndrome caused by a congenital hiatal hernia in a shar-pei dog. Vet Rec 2006;159:322–3. PUBMED Abstract
  270. Lamb CR. Ultrasonographic diagnosis of congenital portosystemic shunts in dogs - results of a prospective study. Vet Radiol Ultrasound 1996;37:281–8.
  271. von Herbay A, Frieling T, Haussinger D. Association between duplex Doppler sonographic flow pattern in right hepatic vein and various liver diseases. J Clin Ultrasound 2001;29:25–30. PUBMED Abstract
  272. Wrigley RH, Macy DW, Wykes PM. Ligation of ductus venosus in a dog, using ultrasonographic guidance. J Am Vet Med Assoc 1983;183:1461–4. PUBMED Abstract
  273. Wrigley RH, Konde LJ, Park RD, et al. Ultrasonographic diagnosis of portacaval shunts in young dogs. J Am Vet Med Assoc 1987;191:421–4. PUBMED Abstract
  274. Lamb CR, Forster-van Hijfte MA, White RN, et al. Ultrasonographic diagnosis of congenital portosystemic shunt in 14 cats. J Small Anim Pract 1996;37:205–9. PUBMED Abstract
  275. Santilli RA, Gerboni G. Diagnostic imaging of congenital porto-systemic shunts in dogs and cats: a review. Vet J 2003;166:7–18. PUBMED Abstract
  276. Szatmári V, Rothuizen J. Ultrasonographic identification and characterization of congenital portosystemic shunts and portal hypertensive disorders in dogs and cats. In: WSAVA Standards for Clinical and Histopathological Diagnosis of Canine and Feline Liver Disease. WSAVA. Spain: Saunders Elsevier; 2006. p. 15–39.
  277. Berent AC, Tobias KM. Portosystemic Vascular Anomalies. Vet Clin Small Anim 2009;39:513–41. PUBMED Abstract
  278. Tivers M, Lipscomb V. Congenital portosystemic shunts in cats. Investigation, diagnosis and stabilisation. J Feline Med Surg 2011;13:173–84.
  279. Martin RA. Congenital portosystemic shunts in the dog and cat. Vet Clin North Am Small Anim Pract 1993; 23:609–23. PUBMED Abstract
  280. van den Ingh TS, Rothuizen J, Meyer HP. Circulatory disorders of the liver in dogs and cats. Vet Q 1995; 17:70–6. PUBMED Abstract
  281. van Straten G, Leegwater PA, de Vries M, et al. Inherited congenital extrahepatic portosystemic shunts in Cairn terriers. J Vet Intern Med 2005;19:321–4. PUBMED Abstract
  282. van Steenbeek FG, Leegwater PAJ, van Sluijs FJ, et al. Evidence of inheritance of intrahepatic portosystemic shunts in Irish Wolfhounds. J Vet Intern Med 2009; 23:950–2. PUBMED Abstract
  283. White RN, Forster-van Hijfte MA, Petrie G, et al. Surgical treatment of intrahepatic portosystemic shunts in six cats. Vet Rec 1996;139:314–17. PUBMED Abstract
  284. Lamb CR, White RN. Morphology of congenital intrahepatic portacaval shunts in dogs and cats. Vet Rec 1998;142:55–60. PUBMED Abstract
  285. Weisse C, Schwartz K, Stronger R, et al. Transjugular coil embolization of an intrahepatic portosystemic shunt in a cat. J Am Vet Med Assoc 2002;221:1287–91, 1266-7. PUBMED Abstract
  286. Tillson DM, Winkler JT. Diagnosis and treatment of portosystemic shunts in the cat. Vet Clin North Am Small Anim Pract 2002;32:881–99, vi-vii. PUBMED Abstract
  287. D'Anjou MA. The sonographic search for portosystemic shunts. Clin Tech Small Anim Pract 2007;22: 104–14. PUBMED Abstract
  288. Windsor RC, Olby NJ. Congenital portosystemic shunts in five mature dogs with neurological signs. J Am Anim Hosp Assoc 2007;43:322–31. PUBMED Abstract
  289. Partington BP, Partington CR, Biller DS, et al. Transvenous coil embolization for treatment of patent ductus venosus in a dog. J Am Vet Med Assoc 1993;202:281–4. PUBMED Abstract
  290. Moon ML. Diagnostic imaging of portosystemic shunts. Semin Vet Med Surg (Small Anim) 1990;5:120–6. PUBMED Abstract
  291. Holt DE, Schelling CG, Saunders HM, et al. Correlation of ultrasonographic findings with surgical, portographic, and necropsy findings in dogs and cats with portosystemic shunts: 63 cases (1987-1993). J Am Vet Med Assoc 1995;207:1190–3. PUBMED Abstract
  292. Tiemessen I, Rothuizen J, Voorhout G. Ultrasonography in the diagnosis of congenital portosystemic shunts in dogs. Vet Q 1995;17:50–3. PUBMED Abstract
  293. Salwei RM, O'Brien RT, Matheson JS. Use of contrast harmonic ultrasound for the diagnosis of congenital portosystemic shunts in three dogs. Vet Radiol Ultrasound 2003;44:301–5. PUBMED Abstract
  294. Szatmári V, Rothuizen J, van den Ingh TS, et al. Ultrasonographic findings in dogs with hyperammonemia: 90 cases (2000-2002). J Am Vet Med Assoc 2004;224: 717–27. PUBMED Abstract
  295. Breznock EM, Whiting PG. Portacaval shunts and anomalies. In: Slatter DH, editor. Textbook of small animal surgery. Philadelphia: WB Saunders; 1985. p. 1156.
  296. Scavelli TD, Hornbuckle WE, Roth L, et al. Portosystemic shunts in cats: seven cases (1976-1984). J Am Vet Med Assoc 1986;189:317–25. PUBMED Abstract
  297. Berger B, Whiting PG, Breznock EM, et al. Congenital feline portosystemic shunts. J Am Vet Med Assoc 1986; 188:517–21. PUBMED Abstract
  298. Van den Ingh TS, Rothuizen J, Meyer HP. Portal hypertension associated with primary hypoplasia of the hepatic portal vein in dogs. Vet Rec 1995;137:424–7. PUBMED Abstract
  299. DeMarco J, Center SA, Dykes N, et al. A syndrome resembling idiopathic noncirrhotic portal hypertension in 4 young Doberman pinschers. J Vet Intern Med 1998; 12:147–56. PUBMED Abstract
  300. Bunch SE, Johnson SE, Cullen JM. Idiopathic noncirrhotic portal hypertension in dogs: 33 cases (1982- 1998). J Am Vet Med Assoc 2001;218:392–9. PUBMED Abstract
  301. Schermerhorn T, Center SA, Dykes NL, et al. Characterization of hepatoportal microvascular dysplasia in a kindred of cairn terriers. J Vet Intern Med 1996;10: 219–30. PUBMED Abstract
  302. Christiansen JS, Hottinger HA, Allen L, et al. Hepatic microvascular dysplasia in dogs: a retrospective study of 24 cases (1987-1995). J Am Anim Hosp Assoc 2000; 36:385–9. PUBMED Abstract
  303. Gómez-Ochoa P, Llabrés-Díaz F, Ruiz S, et al. Ultrasonographic appearance of the intravascular transit of agitated saline in normal dogs following ultrasound guided percutaneous splenic injection. Vet Radiology Ultrasound 2010;51:523–6. PUBMED Abstract
  304. Gómez-Ochoa P, Llabrés-Díaz F, Ruiz S, et al. Use of transsplenic injection of agitated saline and heparinized blood for the ultrasonographic diagnosis of macroscopic portosystemic shunts in dogs. Vet Radiology Ultrasound 2011;52:103–6. PUBMED Abstract
  305. Youmans KR, Hunt GB. Cellophane banding for the gradual attenuation of single extrahepatic portosystemic shunts in eleven dogs. Aust Vet J 1998;76:531–7. PUBMED Abstract
  306. Gonzalo-Orden JM, Altonaga JR, Costilla S, et al. Transvenous coil embolization of an intrahepatic portosystemic shunt in a dog. Vet Radiol Ultrasound 2000;41: 516–18. PUBMED Abstract
  307. Leveille R, Pibarot P, Soulez G, et al. Transvenous coil embolization of an extrahepatic portosystemic shunt in a dog: a naturally occurring model of portosystemic malformations in humans. Pediatr Radiol 2000; 30:607–9. PUBMED Abstract
  308. Szatmari V, van Sluijs FJ, Rothuizen J, et al. Intraoperative ultrasonography of the portal vein during attenuation of intrahepatic portocaval shunts in dogs. J Am Vet Med Assoc 2003;222:1086–92, 1077. PUBMED Abstract
  309. Weisse C, Mondschein JI, Itkin M, et al. Use of a percutaneous atrial septal occluder device for complete acute occlusion of an intrahepatic portosystemic shunt in a dog. J Am Vet Med Assoc 2005;227:249–52, 236. PUBMED Abstract
  310. Mehl ML, Kyles AE, Case JB, et al. Surgical management of left-divisional intrahepatic portosystemic shunts: outcome after partial ligation of, or ameroid ring constrictor placement on, the left hepatic vein in twenty-eight dogs (1995-2005). Vet Surg 2007;36:21–30. PUBMED Abstract
  311. Bussadori R, Bussadori C, Millan L, et al. Transvenous coil embolisation for the treatment of single congenital portosystemic shunts in six dogs. Vet J 2007. PUBMED Abstract
  312. Furneaux RW. Liver hemodynamics as they relate to portosystemic shunts in the dog: a review. Res Vet Sci 2011;91:175–80. PUBMED Abstract
  313. Kummeling A, Vrakking DJE, Rothuizen J, et al. Hepatic volume measurements in dogs with extrahepatic congenital portosysemic shunts before and after surgical attenuation. J Vet Intern Med 2010;24:114–19. PUBMED Abstract
  314. Bertolini G. Acquired portal collateral circulation in the dog and cat. Vet Radiol Ultrasound 2010;51:25–33. PUBMED Abstract
  315. Strombeck DR, Guilford WG. Small animal gastroenterology. 2nd ed. London: Wolfe; 1991.
  316. Szatmari V, van den Ingh TS, Fenyves B, et al. Portal hypertension in a dog due to circumscribed fibrosis of the wall of the extrahepatic portal vein. Vet Rec 2002; 150:602–5. PUBMED Abstract
  317. Willard MD, Bailey MQ, Hauptman J, et al. Obstructed portal venous flow and portal vein thrombus in a dog. J Am Vet Med Assoc 1989;194:1449–51. PUBMED Abstract
  318. Van Winkle TJ, Bruce E. Thrombosis of the portal vein in eleven dogs. Vet Pathol 1993;30:28–35. PUBMED Abstract
  319. Lamb CR, Wrigley RH, Simpson KW, et al. Ultrasonographic diagnosis of portal vein thrombosis in four dogs. Vet Radiol Ultrasound 1996;37:121–9.
  320. Diaz Espineira MM, Vink-Nooteboom M, Van den Ingh TS, et al. Thrombosis of the portal vein in a miniature schnauzer. J Small Anim Pract 1999;40:540–3. PUBMED Abstract
  321. Bressler C, Himes LC, Moreau RE. Portal vein and aortic thromboses in a Siberian husky with ehrlichiosis and hypothyroidism. J Small Anim Pract 2003;44:408–10. PUBMED Abstract
  322. Respess M, O'Toole TE, Taeymans O, et al. Portal vein thrombosis in 33 dogs: 1998-2011. J Vet Intern Med 2012;26:230–7. PUBMED Abstract
  323. Rogers CL, O'Toole TE, Keating JH, et al. Portal vein thrombosis in cats: 6 cases (2001-2006). J Vet Intern Med 2008;22:282–7. PUBMED Abstract
  324. McConnell JF, Sparkes AH, Ladlow J, et al. Ultrasonographic diagnosis of unusual portal vascular abnormalities in two cats. J Small Anim Pract 2006;47:338–43. PUBMED Abstract
  325. Theilen GH, Madewell BR. Veterinary cancer medicine. 2nd ed. Philadelphia: Lea & Febiger; 1987.
  326. Roy RG, Post GS, Waters DJ, et al. Portal vein thrombosis as a complication of portosystemic shunt ligation in two dogs. J Am Anim Hosp Assoc 1992;28:53–8.
  327. Loperfido F, Lombardo A, Amico CM, et al. Doppler analysis of portal vein flow in tricuspid regurgitation. J Heart Valve Dis 1993;2:174–82. PUBMED Abstract
  328. Rengo C, Brevetti G, Sorrentino G, et al. Portal vein pulsatility ratio provides a measure of right heart function in chronic heart failure. Ultrasound Med Biol 1998;24:327–32. PUBMED Abstract
  329. Gorka TS, Gorka W. Doppler sonographic diagnosis of severe portal vein pulsatility in constrictive pericarditis: flow normalization after pericardiectomy. J Clin Ultrasound 1999;27:84–8. PUBMED Abstract
  330. Wachsberg RH, Needleman L, Wilson DJ. Portal vein pulsatility in normal and cirrhotic adults without cardiac disease. J Clin Ultrasound 1995;23:3–15. PUBMED Abstract
  331. Szatmari V, van Sluijs FJ, Rothuizen J, et al. Ultrasonographic assessment of hemodynamic changes in the portal vein during surgical attenuation of congenital extrahepatic portosystemic shunts in dogs. J Am Vet Med Assoc 2004;224:395–402. PUBMED Abstract
  332. Vogt JC, Krahwinkel DJ Jr, Bright RM, et al. Gradual occlusion of extrahepatic portosystemic shunts in dogs and cats using the ameroid constrictor. Vet Surg 1996;25:495–502. PUBMED Abstract
  333. Youmans KR, Hunt GB. Experimental evaluation of four methods of progressive venous attenuation in dogs. Vet Surg 1999;28:38–47. PUBMED Abstract
  334. Broome CJ, Walsh VP, Braddock JA. Congenital portosystemic shunts in dogs and cats. N Z Vet J 2004;52:154–62. PUBMED Abstract
  335. Szatmari V, Rothuizen J, van Sluijs FJ, et al. Ultrasonographic evaluation of partially attenuated congenital extrahepatic portosystemic shunts in 14 dogs. Vet Rec 2004;155:448–56. PUBMED Abstract
  336. McConnell JF, Sparkes AH, Ladlow J, et al. Ultrasonographic diagnosis of unusual portal vascular abnormalities in two cats. J Small Anim Pract 2006;47:338–43. PUBMED Abstract
  337. Ohnishi K, Saito M, Nakayama T, et al. Portal venous hemodynamics in chronic liver disease: effects of posture change and exercise. Radiology 1985;155:757–61. PUBMED Abstract
  338. Legendre AM, Krahwinkel DJ, Carrig CB, et al. Ascites associated with intrahepatic arteriovenous fistula in a cat. J Am Vet Med Assoc 1976;168:589–91. PUBMED Abstract
  339. Bailey MQ, Willard MD, McLoughlin MA, et al. Ultrasonographic findings associated with congenital hepatic arteriovenous fistula in three dogs. J Am Vet Med Assoc 1988;192:1099–101. PUBMED Abstract
  340. Szatmari V, Nemeth T, Kotai I, et al. Doppler ultrasonographic diagnosis and anatomy of congenital intrahepatic arterioportal fistula in a puppy. Vet Radiol Ultrasound 2000;41:284–6. PUBMED Abstract
  341. Koide K, Koide Y, Wada Y, et al. Congenital hepatic arteriovenous fistula with intrahepatic portosystemic shunt and aortic stenosis in a dog. J Vet Med Sci 2004;66:299–302. PUBMED Abstract
  342. Zwingenberger AL, McLear RC, Weisse C. Diagnosis of arterioportal fistulae in four dogs using computed tomographic angiography. Vet Radiol Ultrasound 2005;46:472–7. PUBMED Abstract
  343. Chanoit G, Kyles AE, Weisse C, et al. Surgical and interventional radiographic treatment of dogs with hepatic arteriovenous fistulae. Vet Surg 2007;36:199–209. PUBMED Abstract